Functional
Foods
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Functional Foods
Functional foods and nutraceuticals are broad terms that describe foods, food ingredients or dietary supplements that demonstrate specific health or medical benefits, including the prevention and treatment of disease, beyond basic nutritional functions. These products include whole foods, food additives, vitamin and mineral supplements, herbs, phytonutrients, and probiotics. Nutraceuticals can be derived from plant, animal, marine and microbial sources. (source = agriculture Canada)
. Visit the individual diseases/conditions pages listed on the main menu to find info on functional foods linked to the prevention of these diseases. Note: All external links open in a new window, so you can see the originating URL and/or visit the originating site. HealthyEating.net remains open in a separate window.

General Info/ Types/ Benefits

Phytochemicals

Phytochemicals are nonnutritive plant chemicals that contain protective, disease-preventing compounds. More than 900 different phytochemicals have been identified as components of food. Research into the disease-fighting properties of plant chemicals continues to make headlines daily. Sort the facts from the "phyto-fiction" by reviewing the resources below.

Functional Foods as Antioxidants

Specific Functional Foods Info:

Functional Foods Chart
(not an all-inclusive list)

Class
Subclasses
Health Benefits
Food Sources
Dietary Fiber -Insoluble Fiber -may reduce risk of breast or colon cancers -wheat bran, whole grains, many fruits and vegetables
  -Soluble Fiber -reduces risk of cardiovascular disease -oats, apples, beans & other fruits and vegetables
       
Fatty Acids Omega-3 fatty acids - DHA/EPA -may reduce risk of CVD & improve mental, visual functions -tuna; fish and marine oils, flax seeds
  Conjugated Linoleic acid (CLA) -may improve body composition, may decrease risk of certain cancers -cheese, meat products
       
Lipoic Acid & Ubiquinone (Coenzyme Q)
  -are antioxidants that extend effects of other antioxidants
-lipoic acid is protective of vit E and C
-also protective of catalase and gluthathione, which are involved in liver detoxification
 
       
Phenols
-protect plants from oxidative damage & do same for humans
-aids vs allegies, inflammation, free radicals, ulcers, viruses and tumours, high blood pressure, platelet stickiness which can contribute to heart disease
-also reduce estrogen production and reduces risk of estrogen-induced cancers.
-may impair development of cataracts in people with diabetes

-found in wine, tea, grapes and wide variety of other plants
-
blue, blue-red and violet colours seen in berries (bilberries), grapes, wine and purple eggplant due to phenolic properties.

  Caffeic & Ferulic Acids: -may prevent the formation of carcinogens in the stomach -fruits, vegetables, citrus
  Carnosol: -an antioxidant that may prevent cholesterol oxidation and prevent cancer. -rosemary
 

Catechins, Gallic Acids:
- differ in chemical structure from other flavinoids but share same chemopreventive properties
most common catechins are gallic esters below:

   
  -epicatechin (EC) -neutralize free radicals, may reduce risk of cancer -green tea (camellia sinensis)
  -epicatechin gallate (ECG) -neutralize free radicals, may reduce risk of cancer -green tea (camellia sinensis)
  -epigallocatechin gallate (EGCG) -neutralize free radicals, may reduce risk of cancer -green tea (camellia sinensis)
 

Flavonoids
-previously referred to as vitamin P
-more than 1500 different types including those listed below:

  -green veggies, kale, spinach
  Anthocyanins & Anthocyanidins -neutralize free radicals, may reduce risk of cancer -brightly coloured fruits & veggies: berries, eggplant skin, red cabbage
  Catechins -neutralize free radicals, may reduce risk of cancer -tea, grapes, wine
  Flavanones:
-hesperidin
-silybin
-xanthohumol
-neutralize free radicals, may reduce risk of cancer -citrus, milk thistle, beer hops
  Flavones:
-apigenin
-neutralizes free radicals, may reduce risk of cancer -celery, parsley, apples
 

Flavonols:
-quercetin
-rutin
-ginkgoflavonglycosides

  -grapefruit, buckwheat, ginkgo, grapes, wine, onions
 

Phytoestrogens
-found in most plant varieties
-includes:

-block uptake of cholesterol and speed excretion of it from body
-may protect vs cancers of the colon, breast and prostate

-seeds of green & yellow vegetables including: pumpkins, yams, soy, rice and herbs
 

Isoflavones:
-function much like flavonoids (see below)
-includes following types:

  -soybeans & soy-based foods & other legumes
  genistein and daidzein -may protect vs heart disease and some cancers; may lower LDL cholesterol -in soy products and herb Kudzu
  Lignans -Plant phenolics converted in the intestines to a type of phytoestrogen ("plant" estrogen) with antioxidant properties. As a weak estrogen, lignans may reduce risk of hormone-related cancers by tying up the estrogen receptors on cells.
-lowers LDL & total cholesterol & triglycerides
-flax or sesame seeds and flour, rye, whole grain products, vegetables and some berries
       
Plant Sterols Stanol Ester -lowers blood cholesterol levels by inhibiting cholesterol absorption -corn, soy, wheat, wood oils, nuts, sesame or sunflower seeds
       
Prebiotic & Probiotics Fructo-oligosaccharides (FOS) -may improve gastrointestinal health -Jerusalem artichokes, shallots, onion powder
  Lactobacillus -may improve gastrointestinal health -yogurt, other dairy
       
Saponins   -may help control blood cholesterol, triglycerides and blood sugar
-contains anticancer enzymes
-soybeans, soy foods, soy protein-containing foods, beans
       
Soy Protein   -25 grams per day may reduce risk of heat disease -soybeans and soy-based foods
       
Terpenes -one of largest classes
-a family of chemical substances in the essential oils of plants
-found in many plant varieties
-protect plants from oxygen damage that attacks human cells
-act as antioxidants, protecting fats, blood and other body fluids from free radical damage -tomatoes, parsley, oranges, pink grapefruit, spinach, red palm oil
  Carotenoids:
-bright yellow, orange & red plant pigments
-includes
-serves as antioxidant by neutralizing cancer-promoting free-radicals that can damage healthy cells
-may protect vs lung, breast, colorectal, uterine and prostate cancers
 
  -alpha carotene:
-antioxidant that body changes to vitamin A as needed
-linked to reduced risk of lung cancer
-carrots,
  -beta carotene -antioxidant that body changes to vitamin A as needed
-may play a role in slowing progression of lung and oral cancers
-carrots, dark leafy greens & other red, orange and yellow fruits & veggies
  -lutein -a powerful antioxidant and one of two carotenoids found in the eye. These yellow pigments are believed to filter out harmful blue light and protect against age-related macular degeneration, the leading cause of blindness in people over 65
-more resistant to cooking than other carotenoids, it's also associated with decreased lung cancer risk.
-green vegetables like spinach and collard greens
  -lycopene:
-gives red colour to tomatoes, guava, rosehip, watermelon, and pink grapefruit
-helps reduce risk of macular degenerative disease, serum lipid oxidation and cancers of the lung, bladder, cervix, and skin. -lycopene in tomatos absorbed better from tomato products such as juices, sauces, paste and ketchup
  zeaxanthin -helps maintain healthy eyesight -eggs, citrus, corn
  Limonoids:
-it is used in Japan to dissolve gallstones
-protects lung tissue
-citrus peels/oils, as well as garlic and the oils of other plants
       
Thiols Organo or Allylic Sulfides:
-these compounds are released when foods are cut or smashed
-includes:

-process antimutagenic and anticarcinogenic properties, as well as immune and cardiovascular protection
-offer antigrowth activity for tumors, fungi, parasites and cholesterol
-activate liver detoxification enzyme systems

-garlic, onions, leeks, shallots, chives,
  Allyl methyl trisulfide -may boost enzyme cancer detox systems and prevent bacteria from converting nitrates into substances that help make carcinogens -onions, garlic, olives, leeks, scallions
  Diallyl sulfide -may boost enzyme cancer detox systems and prevent bacteria from converting nitrates into substances that help make carcinogens -onions, garlic, olives, leeks, scallions
  -Glucosinolates including isothiocyanates, dithiolthiones, and sulforaphane

-powerful activators of liver detoxification enzymes and protect vs cancers of the breast, liver, colon, lung, stomach and esophagus
-also regulate white blood cells and immune system

-cruciferous vegetables
       
Tocotrienols & Tocopherols
-alpha tocopherol is most common form of vitamin E, found in both body and in supplements
-gamma tocopherol is primary source of vitamin E in diet
-tocotrienols appear to inhibit breast cancer
-tocopherols do not appear to have the same preventative effect
-in grains, palm oil

Sources:

Background on Functional Foods by IFIC

Doctoring Your Meals with Functional Foods by Eileen Peters, MS, RD/NWU Medical School

Lycopene: The Facts by Lycopene.org

Phytochemicals: Nutrients of the Future by Marcia Zimmerman, C.N.


Interactive Tools:

Databases:


Websites
The sites and programs listed are recommended as information resources for visitors. HealthyEating.net is not responsible for accuracy of content, and inclusion in this list is not an endorsement by HealthyEating.net.

Canadian:

  • Agriculture Canada's Functional Foods & Nutraceuticals- This site highlights the capabilities of approximately 100 Canadian companies and research organisations and is intended to help companies and distributors seeking partners or reliable, well characterized products. It can also be used by people who want to know more about the sector and to facilitate networking and alliances among companies and research organisations.
  • Nutraceuticals and Functional Foods Institute (INAF)- regroups researchers and scientists working to the advancement of knowledge in human nutrition and the effects on the health. Among others, their works are directed toward the effects of nutraceuticals products and functional foods on reduction of chronicle disease.

U.S.:

  • BHNRC's Phytonutrient Laboratory - the mission of the Phytonutrients Laboratory is to:delineate the metabolism in humans of phytonutrients that are present in foods;understand the roles of these compounds in health promotion; andprovide information relative to the intake of fruits, vegetables, and grains for the diverse population of adult Americans.
  • H.J. Heinz Company's Lycopene.org - site maintained by the Heinz Institute of Nutritional Sciences, and is funded by an educational grant from the H.J. Heinz Company. Your primary source of information on lycopene.
  • Lutein Information Bureau - encourages visitors to look at lutein and its role in vision and overall health.
  • University of Illinois' Functional Foods: Beyond Basic Nutrition - Functional Foods for Health, a joint program of the University of Illinois at Chicago and the University of Illinois at Urbana-Champaign, is dedicated to the improvement of human health through multi-disciplinary research, education, and communication focused on the identification of safe and efficacious foods and other physiologically active natural products which may reduce chronic disease risk or promote optimal health.

Around the World-By Continent:

Europe:

  • Swedish Center of Excellence and Innovation in Functional Foods - This website is Sweden's leading on-line functional foods community for researchers in industry and Academia, consumers organizations, authorities, politicians and venture capital enterprises, providing online access to scientific databases, news alerts and other information services to over 800 registered users.
  • International Food Information Service (UK) - a not-for-profit organisation, established in 1968, which: provides information products and services; commissions research in information science; and provides education in information science for the international food science, food technology and human nutrition community.

Oceania:

  • Southern Cross Universities Centre for Phtochemistry (Australia) - Established in February 1999, the Centre for Phytochemistry is a leading authority in natural product chemistry and is rapidly developing a reputation as a centre of excellence in the research and development of medicinal and functional plant extracts.

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